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Synthesis and Identification of Novel Potential Molecules Against COVID-19 Main Protease Through Structure-Guided Virtual Screening Approach

Youness El Bakri, El Hassane Anouar, Sajjad Ahmad, Amal A. Nassar, Mohamed Labd Taha, Joel T. Mague, Lhoussaine El Ghayati, El Mokhtar Essassi

2021Applied Biochemistry and Biotechnology15 citationsDOIOpen Access PDF

Topics & Concepts

ProteaseDocking (animal)Virtual screeningIn silicoCoronavirusMolecular dynamicsChemistryComputational biologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Active siteSmall moleculeAmino acidBinding siteDrug discoveryCoronavirus disease 2019 (COVID-19)AutoDockCombinatorial chemistryStereochemistryBiochemistryEnzymeBiologyComputational chemistryInfectious disease (medical specialty)MedicinePathologyDiseaseGeneNursingComputational Drug Discovery MethodsSynthesis and biological activitySARS-CoV-2 and COVID-19 Research
Synthesis and Identification of Novel Potential Molecules Against COVID-19 Main Protease Through Structure-Guided Virtual Screening Approach | Litcius