Hydroxychloroquine suppresses lung tumorigenesis via inducing FoxO3a nuclear translocation through STAT3 inactivation
Xin Lyu, Lizhong Zeng, Hua Zhang, Yue Ke, Xuan Liu, Nannan Zhao, Jingyan Yuan, Guoan Chen, Shuanying Yang
Topics & Concepts
Cancer researchIn vivoApoptosisCell cycleCarcinogenesisDownregulation and upregulationBiologySTAT3AdenocarcinomaSignal transductionHydroxychloroquineChemistryCancerCell biologyInternal medicineMedicineGeneBiochemistryDiseaseCoronavirus disease 2019 (COVID-19)GeneticsInfectious disease (medical specialty)BiotechnologyFOXO transcription factor regulationCancer Mechanisms and TherapyHeat shock proteins research