Synthesis of 3-nitroindoles by sequential paired electrolysis
Ashley C. Lindsay, Paul A. Kilmartin, Jonathan Sperry
Abstract
) to the iodine radical (I˙), which facilitates cyclisation of the nitroenamine to give a 3-nitroindolinyl radical. Cathodic reduction and protonation generates a 3-nitroindoline that upon oxidation forms the 3-nitroindole.
Topics & Concepts
ElectrolysisIodideIodineElectrochemistryChemistryAnodeProtonationCathodic protectionCombinatorial chemistryRedoxInorganic chemistryOrganic chemistryElectrodeElectrolytePhysical chemistryIonRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods