Camptothecin derivatives induce apoptosis and inhibit proliferation of prostate cancer PC-3M cells through downregulation of PI3K/Akt signaling pathway
Yan Zhao, Yijia Zheng, Xin Chen, Rui Du, Zhaowei Yan
Topics & Concepts
CamptothecinPI3K/AKT/mTOR pathwayDownregulation and upregulationProtein kinase BApoptosisChemistryCancer researchProstate cancerSignal transductionCancerCell biologyMedicineBiologyInternal medicineBiochemistryGeneCancer therapeutics and mechanismsDNA Repair MechanismsCell death mechanisms and regulation