Synthesis and biological evaluation of gold(III) Schiff base complexes for the treatment of hepatocellular carcinoma through attenuating TrxR activity
Mianli Bian, Xin Wang, Ying Sun, Wukun Liu
Topics & Concepts
Thioredoxin reductaseChemistryHepatocellular carcinomaReactive oxygen speciesApoptosisCancer researchThioredoxinOxidative stressIn vivoSchiff baseEndoplasmic reticulumReductasePharmacologyBiochemistryEnzymeMedicineStereochemistryBiologyBiotechnologyMetal complexes synthesis and propertiesMetal-Catalyzed Oxygenation MechanismsSynthesis and Biological Evaluation