DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
Louis Hollingsworth, Humayun Sharif, Andrew R. Griswold, Pietro Fontana, Julian Mintseris, Kevin B. Dagbay, João A. Paulo, Steven P. Gygi, Daniel A. Bachovchin, Hao Wu
Topics & Concepts
InflammasomeNLRP1ChemistryC-terminusCell biologyVirologyBiologyBiochemistryApoptosisCaspaseReceptorProgrammed cell deathAmino acidPeptidase Inhibition and AnalysisUbiquitin and proteasome pathwaysInflammasome and immune disorders