Potential Anti-acne: Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) from Central Kalimantan-Indonesia
Susi Novaryatiin, Syahrida Dian Ardhany
Abstract
Acne is a disease of the pilosebaceous unit that causes noninflammatory lesions (open and closed comedones), inflammatory lesions (papules, pustules, and nodules), and varying degrees of scarring. Acne can be caused by several factors such as androgen-mediated stimulation from sebaceous gland activity, follicular hyperkeratinization, hormonal imbalances, inflammation, and bacterial infections. 2,3 Some of the bacteria that cause acne include P. acnes, S. epidermidis, and S. aureus. n Indonesia, around 95-100% of young men and 83-85% of young women suffering from acne. The prevalence of acne in adult women is around 12% and 3% in adult men. In another study, it was found that acne is a skin problem until past adolescence with a higher prevalence of women than men in the age range of 20 years or more. ving antibiotics is one alternative acne treatment that aims to reduce the bacterial population. However, giving antibiotics to acne patients was reported to increase the occurrence of upper respiratory tract infections when compared with acne patients without antibiotic therapy. Besides, it can also cause antibiotic resistance because of the evolutionary adaptation of bacteria. This condition encourages the development of research to explore antimicrobial agents from herbal resources that may provide valuable leads that can be further developed as anti-acne drugs.