G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3
Signe Mathiasen, Tiago Palmisano, Nicole A. Perry, Hannah M. Stoveken, Alex Vizurraga, Dyke P. McEwen, Najeah Okashah, Tobias Langenhan, Asuka Inoue, Nevin A. Lambert, Gregory G. Tall, Jonathan A. Javitch
Topics & Concepts
G protein-coupled receptorAgonistReceptorSignal transductionDopamineNeuroscienceCell biologyHEK 293 cellsG proteinChemistryBiologyBiochemistryReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyPharmacological Effects and Assays