Tunable vicinal, geminal diphosphorylation and C–N bond phosphorylation of enaminones toward divergent phosphorylated ketone derivatives
Dingsheng Cao, Chaoli Wang, Jie‐Ping Wan, Chengping Wen, Yunyun Liu
Abstract
The tunable reactions of enaminones with phosphine oxides/phosphonates in the form of vicinal- and geminal diphosphorylation, C–N bond phosphorylation have been developed, providing new methods for the synthesis of divergent phosphorylated molecules.
Topics & Concepts
GeminalVicinalPhosphorylationChemistryKetoneStereochemistryMedicinal chemistryOrganic chemistryBiochemistryOrganophosphorus compounds synthesisFluorine in Organic ChemistryPhosphorus compounds and reactions