Virtual screening for small-molecule pathway regulators by image-profile matching
Mohammad Hossein Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann Devine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew S. Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer Gale, Rik Derynck, Thomas J. Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger‐Mathason, Anne E. Carpenter
Topics & Concepts
Computational biologyYAP1Phenotypic screeningBiologySmall moleculePhenotypeGeneVirtual screeningBottleneckDrug discoveryPhenocopyComputer scienceBioinformaticsGeneticsTranscription factorEmbedded systemCell Image Analysis TechniquesViral Infectious Diseases and Gene Expression in InsectsAdvanced Fluorescence Microscopy Techniques