Design of peptide-based inhibitor agent against amyloid-β aggregation: Molecular docking, synthesis and in vitro evaluation
Safura Jokar, Mostafa Erfani, Omid Bavi, Saeedeh Khazaei, Mohammad Sharifzadeh, Malihe Hajiramezanali, Davood Beiki, Amir Shamloo
Topics & Concepts
PeptideChemistryAmyloid betaP3 peptideDocking (animal)ThioflavinAutoDockIn vitroBiochemistryFibrilPeptide synthesisCombinatorial chemistryAmyloid precursor proteinAlzheimer's diseaseIn silicoDiseaseMedicineNursingGenePathologyAlzheimer's disease research and treatmentsComputational Drug Discovery MethodsSupramolecular Self-Assembly in Materials