Salivary gland macrophages and tissue-resident CD8 <sup>+</sup> T cells cooperate for homeostatic organ surveillance
Bettina Stolp, Flavian Thelen, Xenia Ficht, Lukas M. Altenburger, Nora Ruef, V. V. G. Krishna Inavalli, Philipp Germann, Nicolas Pagé, Federica Moalli, Andrea Raimondi, Kirsten A. Keyser, S. Morteza Seyed Jafari, Francesca Barone, Matthias S. Dettmer, Doron Merkler, Matteo Iannacone, James Sharpe, Christoph Schlapbach, O. Fackler, U. Valentin Nägerl, Jens V. Stein
Abstract
display a unique continuum of migration modes, which are supported in vivo by tissue macrophages to allow homeostatic patrolling of the complex SMG architecture.
Topics & Concepts
Salivary glandHomeostasisCell biologyBiologyImmunologyPathologyMedicineBiochemistryNeuroinflammation and Neurodegeneration MechanismsT-cell and B-cell ImmunologyImmune Cell Function and Interaction