Primary cardiac undifferentiated pleomorphic sarcoma is associated with TP53 mutation during lack of MDM2 amplification, and targeted sequencing analysis reveals potentially actionable targets
Yayan Cui, Liyuan Han, Jianfeng Shang, Wei Fang, Meng Zhao, Dong Chen, Honggang Liu
Topics & Concepts
CDKN2ACancer researchBiologyFluorescence in situ hybridizationMutationCancerMalignancyCDKN2BComparative genomic hybridizationImmunohistochemistryPathologyMedicineGeneticsGeneImmunologyGenomeChromosomeSarcoma Diagnosis and TreatmentCardiac tumors and thrombiVascular Tumors and Angiosarcomas