Theacrine, a Potent Antidepressant Purine Alkaloid from a Special Chinese Tea, Promotes Adult Hippocampal Neurogenesis in Stressed Mice
Shu‐Hua Ouyang, Yujia Zhai, Yanping Wu, Guo Xie, Guo-En Wang, Zhong‐Fu Mao, HU Hui-hua, Xue-Hua Luo, Wan‐Yang Sun, Lei Liang, Wen‐Jun Duan, Hiroshi Kurihara, Yifang Li, Rong‐Rong He
Abstract
as a common beverage with uses for health care and contribute to the development of theacrine as a potential novel antidepressant medicine.
Topics & Concepts
CREBNeurogenesisAntidepressantTropomyosin receptor kinase BCyclic adenosine monophosphatePharmacologyCorticosteroneNeurotrophic factorsBrain-derived neurotrophic factorHippocampal formationChronic stressHippocampusEndocrinologyInternal medicineMedicineChemistryBiologyNeuroscienceReceptorTranscription factorHormoneBiochemistryGeneTryptophan and brain disordersNeuroscience and Neuropharmacology ResearchStress Responses and Cortisol