Primary COVID-19 vaccine cycle and booster doses efficacy: analysis of Italian nationwide vaccination campaign
Camilla Mattiuzzi, Giuseppe Lippi
Abstract
We provide here an updated analysis of primary COVID-19 vaccination and vaccine booster doses efficacy, emerging from the ongoing Italian nationwide COVID-19 vaccination campaign. Primary COVID-19 vaccination efficacy was 76-92% within 6 months, decreasing to 34-80% after 6 months. Administration of vaccine booster doses decreased SARS-CoV-2 infections by 65%, COVID-19-related hospitalizations and deaths by 69% and 97% compared with vaccine efficacy after 6 months, but also decreased SARS-CoV-2 infections by 39% compared with vaccine efficacy within 6 months. These results suggest that COVID-19 vaccine booster doses are important for restoring vaccine efficacy and further limiting virus circulation.
Topics & Concepts
Booster (rocketry)MedicineVaccinationBooster doseCoronavirus disease 2019 (COVID-19)Vaccine efficacyLimitingSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPediatricsVirologyImmunologyImmunizationInternal medicineOutbreakAntibodyInfectious disease (medical specialty)DiseaseMechanical engineeringAstronomyEngineeringPhysicsSARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyCOVID-19 Clinical Research Studies