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Bitter taste receptor activation by cholesterol and an intracellular tastant

Yoojoong Kim, Ryan H. Gumpper, Yongfeng Liu, D. Dewran Koçak, Yan Xiong, Can Cao, Zhijie Deng, B. Krumm, Manish K. Jain, Shicheng Zhang, Jian Jin, Bryan L. Roth

2024Nature90 citationsDOI

Topics & Concepts

Allosteric regulationAgonistChemistryIntracellularG protein-coupled receptorReceptorTasteLigand (biochemistry)BiochemistryAllosteric modulatorBiophysicsStereochemistryCell biologyBiologyBiochemical Analysis and Sensing TechniquesRNA and protein synthesis mechanismsAdvanced Chemical Sensor Technologies
Bitter taste receptor activation by cholesterol and an intracellular tastant | Litcius