A pH-sensitive nanomedicine incorporating catalase gene and photosensitizer augments photodynamic therapy and activates antitumor immunity
Jing Huang, Zecong Xiao, Gengjia Chen, Tan Li, Yuan Peng, Xintao Shuai
Topics & Concepts
Photodynamic therapyPhotosensitizerNanomedicineCancer researchTumor microenvironmentTumor hypoxiaImmunotherapyCatalaseImmunogenic cell deathImmune systemGenetic enhancementTransfectionReactive oxygen speciesCytotoxic T cellImmunityChemistryImmunologyMedicineIn vitroMaterials scienceOxidative stressGeneRadiation therapyBiochemistryTumor cellsNanotechnologyInternal medicineOrganic chemistryNanoparticleNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesImmunotherapy and Immune Responses