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Ginsenoside Rg1 ameliorates depressive-like behavior by inhibiting NLRP3 inflammasome activation in mice exposed to chronic stress

Hui He, Xiaofang Xie, Xixi Kang, Jinqiang Zhang, Lu Wang, Nan Hu, Lei Xie, Cheng Peng, Zili You

2023European Journal of Pharmacology15 citationsDOI

Topics & Concepts

MicrogliaBehavioural despair testNeurogenesisTail suspension testInflammasomeHippocampal formationAnhedoniaPharmacologyIn vivoNeuroprotectionHippocampusImipramineNeuroinflammationInflammationEndocrinologyChemistryAntidepressantInternal medicineMedicineBiologyCell biologyPathologyAlternative medicineDopamineBiotechnologyTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms
Ginsenoside Rg1 ameliorates depressive-like behavior by inhibiting NLRP3 inflammasome activation in mice exposed to chronic stress | Litcius