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Variance partitioning in spatio-temporal disease mapping models

Maria Franco‐Villoria, Massimo Ventrucci, Håvard Rue

2022Statistical Methods in Medical Research10 citationsDOIOpen Access PDF

Abstract

Bayesian disease mapping, yet if undeniably useful to describe variation in risk over time and space, comes with the hurdle of prior elicitation on hard-to-interpret random effect precision parameters. We introduce a reparametrized version of the popular spatio-temporal interaction models, based on Kronecker product intrinsic Gaussian Markov random fields, that we name the variance partitioning model. The variance partitioning model includes a mixing parameter that balances the contribution of the main and interaction effects to the total (generalized) variance and enhances interpretability. The use of a penalized complexity prior on the mixing parameter aids in coding prior information in an intuitive way. We illustrate the advantages of the variance partitioning model using two case studies.

Topics & Concepts

InterpretabilityVariance (accounting)Computer scienceBayesian probabilityMixing (physics)GaussianMarkov chainVariance-based sensitivity analysisStatisticsMathematicsEconometricsData miningAlgorithmMachine learningArtificial intelligenceOne-way analysis of varianceAnalysis of varianceBusinessQuantum mechanicsPhysicsAccountingStatistical Methods and Bayesian InferenceGenetic Associations and EpidemiologyStatistical Methods and Inference
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