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CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor

Nataliya Prokhnevska, Maria A. Cardenas, Rajesh M. Valanparambil, Ewelina Sobierajska, Benjamin G. Barwick, Caroline S. Jansen, Adriana Reyes Moon, Petra Gregorova, Luke del Balzo, Rachel Greenwald, Mehmet Asım Bilen, Mehrdad Alemozaffar, Shreyas Joshi, Cara Cimmino, Christian P. Larsen, Viraj A. Master, Martin G. Sanda, Haydn Kissick

2022Immunity341 citationsDOIOpen Access PDF

Topics & Concepts

Cytotoxic T cellBiologyCD8Cancer researchEffectorT cellCell biologyImmunologyAntigenImmune systemIn vitroGeneticsImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor | Litcius