Redox-Triggered Switchable Synthesis of 3,4-Dihydroquinolin-2(1<i>H</i>)-one Derivatives via Hydride Transfer/<i>N</i>-Dealkylation/<i>N</i>-Acylation
Xiaoyu Yang, Liang Wang, Fangzhi Hu, Lubin Xu, Sanming Li, Shuai‐Shuai Li
Abstract
-QM involved Michael addition. In addition, the synthetic utility of this protocol has been well illustrated via concise synthesis of CYP11B2 inhibitor.
Topics & Concepts
AcylationChemistryAlkylationHydrideCombinatorial chemistryRedoxSodium hydrideOrganic chemistryCatalysisHydrogenCatalytic C–H Functionalization MethodsSynthesis of Indole DerivativesSulfur-Based Synthesis Techniques