Ultrastructural analysis of wild-type and RIM1α knockout active zones in a large cortical synapse
Katharina Lichter, Mila M. Paul, Martin Pauli, Susanne Schoch, Philip Kollmannsberger, Christian Stigloher, Manfred Heckmann, Anna‐Leena Sirén
Abstract
is more heterogeneous. Thus, RIM1α, besides its role in tight SV docking, is crucial for synaptic architecture and vesicle pool organization in MFBs.
Topics & Concepts
SynapseUltrastructureKnockout mouseBiologyNeuroscienceCell biologyAnatomyGeneticsGeneAdvanced Electron Microscopy Techniques and ApplicationsCellular transport and secretioninterferon and immune responses