Selective transferrin coating as a facile strategy to fabricate BBB-permeable and targeted vesicles for potent RNAi therapy of brain metastatic breast cancer in vivo
Yaohua Wei, Yinping Sun, Jingjing Wei, Xinyun Qiu, Fenghua Meng, Gert Storm, Zhiyuan Zhong
Topics & Concepts
TransferrinIn vivoTransferrin receptorCancer researchBlood–brain barrierTranscytosisPharmacologyChemistryMedicineBiologyBiochemistryInternal medicineReceptorEndocytosisBiotechnologyCentral nervous systemAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDendrimers and Hyperbranched Polymers