Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study
J William L Brown, Nick Cunniffe, Ferrán Prados, Baris Kanber, Joanne Jones, Edward Needham, Zoya Georgieva, David Rog, Owen Pearson, James Overell, David MacManus, Rebecca S. Samson, Jonathan Stutters, Charles ffrench‐Constant, Claudia A. M. Gandini Wheeler‐Kingshott, Carla Moran, Paul D. Flynn, Andrew W. Michell, Robin J.M. Franklin, Siddharthan Chandran, Daniel R. Altmann, Declan Chard, Peter Connick, Alasdair Coles
Topics & Concepts
MedicinePlaceboMultiple sclerosisPopulationBexaroteneAdverse effectInternal medicineClinical endpointRandomized controlled trialPediatricsImmunologyPathologyGeneBiochemistryNuclear receptorTranscription factorChemistryEnvironmental healthAlternative medicineMultiple Sclerosis Research StudiesRetinoids in leukemia and cellular processesVestibular and auditory disorders