Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
Bin Huang, Qiang Guo, Marie L. Niedermeier, Jingdong Cheng, Tatjana Engler, Melanie Maurer, Alexander Pautsch, Wolfgang Baumeister, Florian Stengel, Stefan Kochanek, Rubén Fernández‐Busnadiego
Topics & Concepts
HuntingtinHuntingtin ProteinHuntington's diseaseTrinucleotide repeat expansionChemistryPolyglutamine tractBiophysicsGeneCell biologyBiologyMolecular biologyBiochemistryMutantDiseaseAlleleMedicineInternal medicineGenetic Neurodegenerative DiseasesMuscle Physiology and DisordersMitochondrial Function and Pathology