Libertellenone M, a diterpene derived from an endophytic fungus Phomopsis sp. S12, protects against DSS-induced colitis via inhibiting both nuclear translocation of NF-κB and NLRP3 inflammasome activation
Minmin Fan, Gang Xiang, Jingwei Chen, Jian Gao, Wenwen Xue, Yixuan Wang, Wuhao Li, Lin Zhou, Rui‐Hua Jiao, Yan Shen, Qiang Xu
Topics & Concepts
InflammasomeProinflammatory cytokineColitisIn vivoChemistryCaspase 1NF-κBIn vitroMicrobiologyCytokineInflammationBiologyBiochemistryApoptosisImmunologyReceptorBiotechnologyInflammasome and immune disordersNatural product bioactivities and synthesisHerbal Medicine Research Studies