Overcoming resistance to oncolytic virus M1 by targeting PI3K-γ in tumor-associated myeloid cells
Yang Liu, Cuiying Xu, Xiaoting Xiao, Yinting Chen, Xiaobo Wang, Wenfeng Liu, Yaqian Tan, Wenbo Zhu, Jun Hu, Jiankai Liang, Guangmei Yan, Yuan Lin, Jing Cai
Topics & Concepts
Oncolytic virusImmunosuppressionCancer researchImmune systemMyeloidCD8BiologyPI3K/AKT/mTOR pathwayImmunologyCytotoxic T cellCell biologySignal transductionIn vitroBiochemistryVirus-based gene therapy researchCAR-T cell therapy researchRNA Interference and Gene Delivery