A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
He Yan, Yunjie Wen, Zimu Tian, Nathan Hart, Song Han, Steven J. Hughes, Yong Zeng
Topics & Concepts
Extracellular vesiclesRolling circle replicationLoop-mediated isothermal amplificationmicroRNAMolecular biologyEndonucleaseCancer biomarkersComputational biologyBiologyChemistryCell biologyCancerDNABiochemistryGeneGeneticsDNA replicationExtracellular vesicles in diseaseMicroRNA in disease regulationAdvanced biosensing and bioanalysis techniques