Improved nanoformulation and bio-functionalization of linear-dendritic block copolymers with biocompatible ionic liquids
Christine M. Hamadani, Indika Chandrasiri, Mahesh Loku Yaddehige, Gaya S. Dasanayake, Iyanuoluwani Owolabi, Alex S. Flynt, Mehjabeen Hossain, Lucy Liberman, Timothy P. Lodge, Thomas A. Werfel, Davita L. Watkins, Eden E. L. Tanner
Abstract
the linear-dendritic nanoparticles. These results suggest that by controlling the physical chemistry of polymer-IL interactions and assembly on the nanoscale, biological function can be tailored toward the development of more effective and more precisely targeted therapies.
Topics & Concepts
PLGADrug deliverySurface modificationChemistryDrug carrierCopolymerNanoparticleMaterials scienceChemical engineeringNanotechnologyBiophysicsPolymerOrganic chemistryEngineeringPhysical chemistryBiologyIonic liquids properties and applicationsSurfactants and Colloidal SystemsInnovative Microfluidic and Catalytic Techniques Innovation