Litcius/Paper detail

A new beta cell-specific mitophagy reporter mouse shows that metabolic stress leads to accumulation of dysfunctional mitochondria despite increased mitophagy

Kyota Aoyagi, Shun‐ichi Yamashita, Yoshihiro Akimoto, Chiyono Nishiwaki, Yoko Nakamichi, Haruhide Udagawa, Manabu Abe, Kenji Sakimura, Tomotake Kanki, Mica Ohara‐Imaizumi

2022Diabetologia23 citationsDOIOpen Access PDF

Topics & Concepts

MitophagyMitochondrionCell biologyAutophagyGene knockdownBiologyBeta cellIsletChemistryEndocrinologyBiochemistryInsulinApoptosisAutophagy in Disease and TherapyPancreatic function and diabetesMitochondrial Function and Pathology
A new beta cell-specific mitophagy reporter mouse shows that metabolic stress leads to accumulation of dysfunctional mitochondria despite increased mitophagy | Litcius