The Emerging Field of Cardioimmunology: Past, Present and Foreseeable Future
Douglas L. Mann
Abstract
Over the past 30 years, the field of cardioimmunology has moved from being dismissed as a field that was chasing an epiphenomenon of little biological consequence to a scientific discipline that is providing important new insights into the immunologic basis for hypertension, atherosclerosis, myocarditis, pericarditis, autoimmune heart disease, and heart failure. In this article, we will review the conceptual insights and technical breakthroughs that have allowed the field to move forward, as well as the clinical trials in the cardioimmunology space, to provide a historical context for the articles that will appear in the compendium that is focused on the interface between cardioimmunology, myocardial function, and disease.
Topics & Concepts
Context (archaeology)MyocarditisCompendiumField (mathematics)DiseaseEpiphenomenonHeart failureMedicineEngineering ethicsIntensive care medicineEpistemologyPathologyCardiologyEngineeringBiologyHistoryPhilosophyPure mathematicsMathematicsArchaeologyPaleontologyViral Infections and Immunology ResearchCardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases