Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial

Emil Lou, Modassir S Choudhry, Timothy K. Starr, Timothy D. Folsom, Jason Bell, Blaine Rathmann, Anthony P. DeFeo, Ji‐Hyun Kim, Nicholas J. Slipek, Zhao-Hui Jin, Darin Sumstad, Christopher A. Klebanoff, Katherine J. Ladner, Akshat Sarkari, R. Scott McIvor, Thomas A. Murray, Jeffrey S. Miller, Madhuri Rao, Eric H. Jensen, Jacob S. Ankeny, Mahmoud A. Khalifa, Anil Chauhan, Benjamin Spilseth, Ajay Dixit, Paolo P. Provenzano, Wenjing Pan, Daniel Weber, Miranda Byrne‐Steele, Tom Henley, David H. McKenna, Matthew J. Johnson, Beau R. Webber, Branden S. Moriarity