Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture
Michelle Riegman, Liran Sagie, Chen Galed, Tom Levin, Noah J. Steinberg, Scott J. Dixon, Ulrich Wiesner, Michelle S. Bradbury, Philipp Niethammer, Assaf Zaritsky, Michael Overholtzer
Topics & Concepts
PyroptosisProgrammed cell deathCell biologyGPX4NecroptosisCellApoptosisChemistryIntracellularCell membraneCell damageLipid peroxideBiologyGlutathioneBiochemistryOxidative stressLipid peroxidationGlutathione peroxidaseEnzymeFerroptosis and cancer prognosisHeme Oxygenase-1 and Carbon MonoxideInflammasome and immune disorders