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C5 inhibition with eculizumab prevents thrombotic microangiopathy in a case series of pig-to-human kidney xenotransplantation

Maggie E. Jones, Huma Fatima, Vineeta Kumar, Douglas J. Anderson, Julie A. Houp, Jackson Perry, Gavin Baker, Leigh McManus, Andrew J. Shunk, Paige M. Porrett, Jayme E. Locke

2024Journal of Clinical Investigation39 citationsDOIOpen Access PDF

Topics & Concepts

EculizumabThrombotic microangiopathyXenotransplantationKidneyMedicineImmunologyPathologyInternal medicineComplement systemTransplantationAntibodyDiseaseXenotransplantation and immune responseOrgan Donation and TransplantationOrgan Transplantation Techniques and Outcomes
C5 inhibition with eculizumab prevents thrombotic microangiopathy in a case series of pig-to-human kidney xenotransplantation | Litcius