Chemical Constituents and Pharmacological Activities of Steroid Saponins Isolated from Rhizoma Paridis
Fen Liu, Luning Li, Xinchen Tian, Dengtian Zhang, Wenxue Sun, Shulong Jiang
Abstract
Rhizoma Paridis, the rhizome of liliaceous plants Paris polyphylla, is one of the most commonly used herbal drugs in China. Phytochemical and pharmacological studies have shown that steroid saponins were the major effective ingredients of Rhizoma Paridis to exert antitumor, anti-inflammatory, hemostasis, and antifibrosis functions. In this review, we discussed the chemical structures of steroid saponins and their related biological activity and mechanisms in cellular and animal models, aiming to provide a reference for future comprehensive exploitation and development of saponins.
Topics & Concepts
ChemistryRhizomePhytochemicalSaponinTraditional medicineSteroidPharmacologyBiochemistryBiologyHormonePathologyAlternative medicineMedicinePhytochemical Studies and BioactivitiesNatural product bioactivities and synthesisChromatography in Natural Products