IL-35 promotes EMT through STAT3 activation and induces MET by promoting M2 macrophage polarization in HCC
Yuan He, Jinhong Pei, Xueqing Li, Gang Chi
Topics & Concepts
Epithelial–mesenchymal transitionMacrophage polarizationTumor microenvironmentMetastasisCancer researchSTAT3CarcinogenesisHepatocellular carcinomaMacrophageM2 MacrophageTumor-associated macrophageTumor progressionChemistryMesenchymal stem cellBiologyPhosphorylationMedicineCancerCell biologyTumor cellsInternal medicineIn vitroBiochemistryImmune cells in cancerCancer Cells and MetastasisEpigenetics and DNA Methylation