Nanosonodynamic effect-promoted mitochondrial dysfunction augments calcium overload for Gasdermin E-induced pyroptotic antitumor therapy
Zheng Zhang, Xin Zhang, Shuangshuang Zhao, Caihong Dong, Wei Feng, Luodan Yu, Li Ding, Yu Chen, Baoding Chen
Topics & Concepts
PyroptosisSonodynamic therapyChemistryCancer researchMitochondrionProgrammed cell deathReactive oxygen speciesCancer cellApoptosisCalciumCell biologyCancerBiochemistryBiologyMedicineInternal medicineOrganic chemistryInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideExtracellular vesicles in disease