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TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2

Chuanbin Yang, Jia Liu, Benjamin Chun‐Kit Tong, Ziying Wang, Zhou Zhu, Cheng-Fu Su, Sravan Gopalkrishnashetty Sreenivasmurthy, Jia-Xi Wu, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Shiying Huang, King‐Ho Cheung, Ju‐Xian Song, Jieqiong Tan, Jiahong Lu, Min Li

2021Acta Pharmacologica Sinica28 citationsDOI

Topics & Concepts

TFEBAutophagyCell biologyApoptosisBiologyLysosomeProgrammed cell deathReactive oxygen speciesRegulatorChemistryBiochemistryGeneEnzymeAutophagy in Disease and TherapyRNA regulation and diseaseRNA Interference and Gene Delivery
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 | Litcius