PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
Jae Jin Kim, Seo Yun Lee, Ji Hye Choi, Hyun Goo Woo, Blerta Xhemalçe, Kyle M. Miller
Topics & Concepts
PCAFBiologyAcetylationCancer researchHistoneP300-CBP Transcription FactorsAcetyltransferaseCell biologyHistone acetyltransferaseMolecular biologyGeneticsHistone AcetyltransferasesDNAGeneDNA Repair MechanismsPARP inhibition in cancer therapyCRISPR and Genetic Engineering