Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD
Ming-Yuan Su, Simon A. Fromm, Roberto Zoncu, James H. Hurley
Topics & Concepts
C9orf72HaploinsufficiencyAmyotrophic lateral sclerosisCell biologyBiologyGTPaseFrontotemporal dementiaTrinucleotide repeat expansionGeneticsNeuroscienceMedicinePathologyGenePhenotypeDiseaseDementiaAlleleAmyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and TreatmentsGenetic Neurodegenerative Diseases