Synthesis and anti-Alzheimer potential of novel α-amino phosphonate derivatives and probing their molecular interaction mechanism with acetylcholinesterase
Kandrakonda Yelamanda Rao, Shaik Jeelan Basha, Monika Kallubai, Mothukuru Sreelakshmi, Irla Sivakumar, Gunti Mallikarjuna, Ranay Mohan Yadav, Sandeep Kumar, Rajagopal Subramanyam, Amooru G. Damu
Topics & Concepts
ChemistryAcetylcholinesteraseStereochemistryActive sitePhosphonateDocking (animal)TacrineCombinatorial chemistryEnzymeBiochemistryMedicineNursingCholinesterase and Neurodegenerative DiseasesSynthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activity