Targeting protein conformations with small molecules to control protein complexes
Emmanouil Zacharioudakis, Evripidis Gavathiotis
Topics & Concepts
Small moleculeDrug discoveryRational designProtein functionChemistryFunction (biology)Protein–protein interactionComputational biologyProtein structureBiophysicsBiochemistryCell biologyBiologyGeneGeneticsUbiquitin and proteasome pathways14-3-3 protein interactionsRNA and protein synthesis mechanisms