Combination of air/moisture/ambient temperature compatible organolithium chemistry with sustainable solvents: selective and efficient synthesis of guanidines and amidines
David Elorriaga, Blanca Parra‐Cadenas, Antonío Antiñolo, Fernando Carrillo‐Hermosilla, Joaquín García‐Álvarez
Abstract
Addition of lithium amides (LiNR 2 ) to carbodiimides/nitriles was achieved in sustainable solvents, under air, allowing the synthesis of guanidines/amidines.
Topics & Concepts
ChemistryOrganic chemistryLithium (medication)MoistureOrganolithium compoundsCombinatorial chemistryIonEndocrinologyMedicineDeprotonationCoordination Chemistry and OrganometallicsChemical Synthesis and ReactionsChemical Synthesis and Analysis