Granulocyte-colony stimulating factor (G-CSF) to treat acute-on-chronic liver failure: A multicenter randomized trial (GRAFT study)
Cornelius Engelmann, Adam Herber, Annegret Franke, Tony Bruns, Philipp A. Reuken, Ingolf Schiefke, Alexander Zipprich, Stefan Zeuzem, Tobias Goeser, Ali Canbay, Christoph P. Berg, Jonel Trebicka, Frank Erhard Uschner, Johannes Chang, Tobias Mueller, Niklas Aehling, Moritz Schmelzle, Katrin Splith, Frank Lammert, Christian M. Lange, Christoph Sarrazin, Christian Trautwein, Michael P. Manns, Dieter Häussinger, Jan Pfeiffenberger, Peter R. Galle, Anett Schmiedeknecht, Thomas Berg
Topics & Concepts
MedicineInternal medicineHazard ratioClinical endpointGastroenterologyGranulocyte colony-stimulating factorRandomized controlled trialMulticenter trialLiver transplantationSurrogate endpointLiver functionProportional hazards modelTransplantationSurgeryConfidence intervalMulticenter studyChemotherapyLiver Disease and TransplantationSepsis Diagnosis and TreatmentImmune Response and Inflammation