Co-operative binding of SKP1, Cullin1 and Cullin7 to FBXW8 results in Cullin1-SKP1-FBXW8-Cullin7 functional complex formation that monitors cellular function of β-TrCP1
Sehbanul Islam, Parul Dutta, Kriti Chopra, Osheen Sahay, Srikanth Rapole, Radha Chauhan, Manas Kumar Santra
Topics & Concepts
Skp1Ubiquitin ligaseCullinCell biologyBiologyUbiquitinChemistryBiochemistryGeneUbiquitin and proteasome pathwaysMicrotubule and mitosis dynamics14-3-3 protein interactions