Choline phosphate lipid as an intra-crosslinker in liposomes for drug and antibody delivery under guard
Shengran Li, Xintao Xie, Wenliang Wang, Sangni Jiang, Weikang Mei, Yuanhua Zhang, Sanrong Liu, Xifei Yu
Abstract
CP-lip intra-crosslinked liposomes would solve the key problem of liposome disintegration, thus enhancing the delivery of therapeutics to target sites.
Topics & Concepts
LiposomeCholineDrug deliveryPhosphateDrugChemistryPhosphatidyl cholineDrug carrierPharmacologyPhospholipidBiochemistryMembraneMedicineOrganic chemistryRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryLipid Membrane Structure and Behavior