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Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, <i>in vitro</i> characterization, <i>ex vivo</i> and <i>in vivo</i> assessments

Sadek Ahmed, Maha M. Amin, Sarah Mohamed El-Korany, Sinar Sayed

2022Drug Delivery75 citationsDOIOpen Access PDF

Abstract

) that leads to higher antifungal activity. The above results confirmed the validity of novasomes to improve the corneal permeation and antifungal activity of Fenticonazole Nitrate.

Topics & Concepts

In vivoPermeationEx vivoDesign–ExpertDispersityMaterials scienceChromatographyBiomedical engineeringChemistryPharmacologyMedicineResponse surface methodologyBiochemistryBiologyBiotechnologyPolymer chemistryMembraneAdvanced Drug Delivery SystemsOcular Infections and TreatmentsAntimicrobial agents and applications
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, <i>in vitro</i> characterization, <i>ex vivo</i> and <i>in vivo</i> assessments | Litcius