Ferrocene-labeled and purification-free electrochemical biosensor based on ligase chain reaction for ultrasensitive single nucleotide polymorphism detection
Fang Hu, Wancun Zhang, Wei Meng, Yuxiang Ma, Xianwei Zhang, Ying Xu, Peng Wang, Yueqing Gu
Topics & Concepts
ChemistryBiosensorDNAFerroceneDNA ligaseDetection limitLigase chain reactionDuplex (building)Hybridization probeNucleotideCombinatorial chemistryMolecular biologyPolymerase chain reactionChromatographyBiochemistryElectrochemistryElectrodeGeneBiologyMultiplex polymerase chain reactionPhysical chemistryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryElectrochemical sensors and biosensors