Integrating a covalent probe with ubiquicidin fragment enables effective bacterial infection imaging
Jyotsna Bhatt Mitra, Saurav Chatterjee, Anuj Kumar, Anupam Bandyopadhyay, Archana Mukherjee
Abstract
A covalent probe attached to the UBI antimicrobial peptide enhances membrane binding retention time through iminoboronate formation, thus improving bacterial infection imaging in vivo .
Topics & Concepts
Covalent bondChemistryIn vivoPeptideAntimicrobialAntimicrobial peptidesMembraneCationic polymerizationIn vitroBiophysicsBiochemistryCombinatorial chemistryBiologyOrganic chemistryBiotechnologyOrthopedic Infections and TreatmentsAntimicrobial Peptides and ActivitiesNanoplatforms for cancer theranostics