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Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells

Sofia K. Georgiou‐Siafis, Asterios S. Tsiftsoglou

2020Biochemical Pharmacology25 citationsDOI

Topics & Concepts

HeminHemeKEAP1Cell biologyBiochemistryUbiquitin ligaseHeme oxygenaseChemistryK562 cellsSignal transductionBiologyUbiquitinTranscription factorCellGeneEnzymeGenomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon MonoxideEnergy and Environment Impacts
Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells | Litcius